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Dapagliflozin

Dapagliflozin CAS NO.461432-26-8

Dapagliflozin is a potent and selective SGLT-2(SLC5A2 )inhibitor with EC50 of 1.1 nM. It has good permeability across Caco-2 cell membranes and is a substrate for P-glycoprotein (P-gp). Dapagliflozin is not a significant P-gp inhibitor.

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Features & Specification

Product Name

Dapagliflozin

Synonyms

Dapagliflozin propanediol;
BMS-512148, Forxiga
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol;

CAS No.

461432-26-8

Molecular Structure

 

Mobecular Weight

408.87

Molecular Formula

C21H25ClO6

Key Specification

Appearance:              White to off-white solid
Purity:                   ≥98% by HPLC
Moisture (%):              0.5%Max

Package

25kg/kraft paper bag, fiber drum, carton

Application

Intermediate in organic syntheses

Storage

Store in cool,dry and well-ventilated place,package should be kept sealed.  

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