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Miconazole nitrate

Miconazole nitrate CAS NO.22832-87-7

Miconazole nitrate is an antifungal agent also known as the drug Daktarin which is used to treat skin tinea. Inhibits fungal membrane ergosterol biosynthesis. Increases reactive oxygen species production. Also known as brand name of Decocort / Femizol-M / Gyno-Daktarin / Miconazex / Monistat / Monistat-Derm / Zeasorb-AF / Zimycan.

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Features & Specification

Product Name

Miconazole nitrate

Synonyms

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
Daktarin
Miconazole
Monistat

CAS No.

22832-87-7

Molecular Structure

 

Mobecular Weight

479.14

Molecular Formula

C18H15Cl4N3O4

Key Specification

Appearance:       White or off-white crystalline powder
Purity %(HPLC):     99.0 min
Loss on drying %:    0.5 max
Melting range ℃:   170-185
Solubility:        Slightly soluble in water. Soluble in propylene glycol or pyridine.

Package

25kg/fiber drum, double layer PE plastic bag inside

Application

An imidazole antifungal agent that is used topically and by intravenous infusion, inhibits fungal membrane ergosterol biosynthesis. Increases reactive oxygen species production.
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum;
in the treatment of cutaneous candidiasis (moniliasis);
in the treatment of tinea versicolor.

Storage

Store in cool,dry and well-ventilated place,package should be kept sealed. 

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