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(R)-(+)-2-Tetrahydrofuroic acid

(R)-(+)-2-Tetrahydrofuroic acid CAS NO.87392-05-0

(R)-Tetrahydrofurancarboxylic acid is an important pharmaceutical intermediate, and the effectiveness of its stereoisomers has attracted people's attention. PCBelanger et al. "(Can. J. Chem. 61, 1383 (1983)" first reported an effective resolution method for the compound. However, the method used the extremely toxic and expensive Strychnine from Chemicalbook. (Brucinedihydrate) is used as a resolving agent. In addition, this method also has problems such as low product yield and low recovery rate of the resolving agent. In order to solve these problems, the resolution process can adapt to the needs of industrial production. Researchers have done a lot of research on resolution agents and reaction solvents.

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Features & Specification

Product Name

(R)-(+)-2-Tetrahydrofuroic acid

Synonyms

99% (98% ee) 1GR;(R)-(+)-Tetrahydro-2-furoic acid, 99% (98% ee);(R)-(+)-Tetrahydro-2-furoic acid 99%;(2R)-oxolane-2-carboxylic acid;(R)-(+)-Tetrahydrofuran-2-carboxylic Acid;(R)-(+)-Tetrahydro-2-furoic acid≥ 99% (GC, Chiral purity);(R)-Tetrahydrofuran-2-carboxylic Acid,99%e.e.;(R)-2-TETRAHYDROFUROIC ACID

CAS No.

87392-05-0

Molecular Structure

 

Mobecular Weight

116.12

Molecular Formula

C5H8O3

Key Specification

Appearance:              Colorless to light yellow liquid
Content(%):               98min
Hydroxyl Value(mg KOH/g):   
Moisture (%):               

Package

25kg/ fiber drum

Application

(R) -tetrahydrofuran formic acid can be used in the preparation of Zosin antihypertensive drugs, afzosin, terazosin, prostate cancer drugs, and the synthesis of cephalosporin antibiotic intermediates and chiral adjuvant (R) -acetyltetrahydrofuran.

Storage

Store in cool,dry and well-ventilated place,package should be kept sealed. 

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